Neutron scattering for structural biology

Neutron Protein Crystallography. Hydrogen- and Hydration-sensitive Structural Biology

Neutron protein crystallography (NPC) has not substantially contributed to the determination of the folding structures of biological macromolecules. It takes the next step beyond the folding structure of proteins. This paper demonstrates how hydrogen atoms can be seen by NPC and how NPC can explore protonation and deprotonation of amino acid residues, hydration structures, and hydrogen-to-deute...

Structural characterization of ionic gelator studied by dynamic light scattering and small-angle neutron scattering.

Structural characterization of a hydrogel consisting of an oligomeric electrolyte, poly[pyridinium-1,4-diyliminocarbonyl-1,4-phenylenemethylene chloride] (1-Cl) as an ionic gelator was carried out by static and dynamic light scattering (SLS/DLS) and small-angle neutron scattering (SANS) techniques. All the measurements were performed by changing the concentration and temperature. We have succes...

Small angle neutron scattering

Small Angle Neutron Scattering (SANS) is a technique that enables to probe the 3-D structure of materials on a typical size range lying from ∼ 1 nm up to ∼ a few 100 nm, the obtained information being statistically averaged on a sample whose volume is ∼ 1 cm3. This very rich technique enables to make a full structural characterization of a given object of nanometric dimensions (radius of gyrati...

Neutron Scattering Technique

Neutron scattering technique is the most modern method of sampling the dynamics and structural properties of molecular systems. Neutrons interact with atoms via nuclear which has nuclear forces that are very short ranged. For this reason, neutrons can better penetrate into sample matter and obtain the information that would have been able to by other methods, such as x-rays. In this paper, we s...

Introduction to Neutron Scattering